ESPE Yearbook of Paediatric Endocrinology

Eur J Endocrinol. 2020;183:637–645. doi: 10.1530/EJE-20-0617.This study provides for the first time clear evidence that the block and replace (BR) strategy (combination of carbimazole plus levothyroxine) is not superior to the carbimazole dose titration (DT) strategy for treatment of paediatric Graves’ disease.Wood et al. present the first randomized c...

Brief summary: The authors describe the various applications of the content of ESPE’s e-learning website that has been expanding greatly over the last 10 years. The program includes a Limited Resource Setting module that was developed in 2017 and has been translated into French, Spanish, Swahili, and Chinese.This interesting article retraces the successful development of ESPE’s e-learning program since 2012. Thanks to the tenacity and involveme...

Brief summary: This study describes the genetic and clinical characteristics of 3βHSD2 deficiency in children seen at a single center in Algeria. It describes clinical outcomes, including the frequency of adrenal rest tumors in this population.3β-hydroxysteroid dehydrogenase 2 deficiency (3βHSD2) is a rare form of congenital adrenal hyperplasia. This mixed longitudinal and cross-sectional study was performed in a single Algerian center bet...